オオニシ ジュンジ onishi junji
大西 淳之
- 所属 東京家政大学 栄養学部 管理栄養学科
- 東京家政大学大学院 人間生活学総合研究科 健康栄養学専攻
- 東京家政大学大学院 人間生活学総合研究科 人間生活学専攻
- 東京家政大学短期大学部 短期大学部 栄養科
- 職種 教授
| 論文種別 | 原著 |
| 言語種別 | 英語 |
| 査読の有無 | 査読あり |
| 表題 | Distinct transcriptional and metabolic profiles associated with empathy in Buddhist priests: a pilot study |
| 掲載誌名 | 正式名：Human Genomics |
| 掲載区分 | 国外 |
| 出版社 | BioMed Central |
| 巻・号・頁 | 11,pp.21 |
| 著者・共著者 | Junji OhnishiEmail author, Satoshi Ayuzawa, Seiji Nakamura, Shigeko Sakamoto, Miyo Hori, Tomoko Sasaoka, Eriko Takimoto-Ohnishi, Masakazu Tanatsugu and Kazuo Murakami |
| 担当区分 | 筆頭著者,責任著者 |
| 発行年月 | 2017/09 |
| 概要 | Background
Growing evidence suggests that spiritual/religious involvement may have beneficial effects on both psychological and physical functions. However, the biological basis for this relationship remains unclear. This study explored the role of spiritual/religious involvement across a wide range of biological markers, including transcripts and metabolites, associated with the psychological aspects of empathy in Buddhist priests. Conclusions We performed in vivo phenotyping using transcriptomics, metabolomics, and psychological analyses and found an association between empathy and the phenotype of Buddhist priests in this pilot study. The up-regulation of the anti-viral type I IFN responsive genes and distinct metabolites in the plasma may represent systemic biological adaptations with a unique signature underlying spiritual/religious practices for Buddhists. |