オカベ タクヒロ okabe takuhiro
岡部 拓大
- 所属 東京家政大学 健康科学部 リハビリテーション学科
- 東京家政大学大学院 人間生活学総合研究科 健康栄養学専攻
- 職種 准教授
| 論文種別 | 原著 |
| 言語種別 | 英語 |
| 査読の有無 | 査読あり |
| 表題 | Relationship between bone turnover markers and the heel stiffness index measured by quantitative ultrasound in postmenopausal Japanese women. |
| 掲載誌名 | 正式名：Annals of human biology 略 称：Ann Hum Biol ISSNコード：14645033/03014460 |
| 掲載区分 | 国外 |
| 巻・号・頁 | pp.1-23 |
| 著者・共著者 | Nishimura Takayuki, Arima Kazuhiko, Abe Yasuyo, Kanagae Mitsuo, Mizukami Satoshi, Okabe Takuhiro, Tomita Yoshihito, Goto Hisashi, Hasegawa Maiko, Sou Yoko, Horiguchi Itsuko, Aoyagi Kiyoshi |
| 発行年月 | 2019/04 |
| 概要 | AIM:To investigate the serum TRACP-5b and BAP levels and to determine their associations with the heel stiffness index measured by QUS in postmenopausal women.SUBJECTS AND METHODS:The subjects were 510 postmenopausal women were invited to participate in periodic health examinations in 2011-2013 (the Unzen Study). The heel stiffness index (bone mass) was measured by QUS. Serum samples were collected, and TRACP-5b and BAP levels were measured.RESULTS:Multiple regression analysis showed that a higher log (TRACP-5b) was correlated with a lower stiffness index (p = 0.014), and log (BAP) was not correlated with stiffness index after adjusting for covariates (p = 0.136).CONCLUSION:Higher rates of bone resorption are associated with a lower stiffness index in Japanese postmenopausal women. These results may indicate that high bone resorption affects bone mass more than bone formation, resulting in a low bone mass. |
| DOI | 10.1080/03014460.2019.1607552 |
| PMID | 30995879 |