オカベ タクヒロ  okabe takuhiro
岡部 拓大

  • 所属   東京家政大学  健康科学部 リハビリテーション学科
  •     東京家政大学大学院  人間生活学総合研究科 健康栄養学専攻
  • 職種   准教授
論文種別 原著
言語種別 英語
査読の有無 査読あり
表題 Relationship between bone turnover markers and the heel stiffness index measured by quantitative ultrasound in postmenopausal Japanese women.
掲載誌名 正式名:Annals of human biology
略  称:Ann Hum Biol
ISSNコード:14645033/03014460
掲載区分国外
巻・号・頁 pp.1-23
著者・共著者 Nishimura Takayuki, Arima Kazuhiko, Abe Yasuyo, Kanagae Mitsuo, Mizukami Satoshi, Okabe Takuhiro, Tomita Yoshihito, Goto Hisashi, Hasegawa Maiko, Sou Yoko, Horiguchi Itsuko, Aoyagi Kiyoshi
発行年月 2019/04
概要 AIM:To investigate the serum TRACP-5b and BAP levels and to determine their associations with the heel stiffness index measured by QUS in postmenopausal women.SUBJECTS AND METHODS:The subjects were 510 postmenopausal women were invited to participate in periodic health examinations in 2011-2013 (the Unzen Study). The heel stiffness index (bone mass) was measured by QUS. Serum samples were collected, and TRACP-5b and BAP levels were measured.RESULTS:Multiple regression analysis showed that a higher log (TRACP-5b) was correlated with a lower stiffness index (p = 0.014), and log (BAP) was not correlated with stiffness index after adjusting for covariates (p = 0.136).CONCLUSION:Higher rates of bone resorption are associated with a lower stiffness index in Japanese postmenopausal women. These results may indicate that high bone resorption affects bone mass more than bone formation, resulting in a low bone mass.
DOI 10.1080/03014460.2019.1607552
PMID 30995879